Pregnant woman with ocular myasthenia gravis. A case report

Authors

  • Amado Antonio García Odio Policlínico Universitario Dr. Juan Manuel Páez Inchausti. Isla de la Juventud.
  • Samara Ravelo Nápoles Facultad de Ciencias Médicas de Isla de la Juventud. Isla de la Juventud.
  • Yanisel Rives González Facultad de Ciencias Médicas de Isla de la Juventud. Isla de la Juventud.
  • Daymeris Álvarez Bolivar Facultad de Ciencias Médicas de Isla de la Juventud. Isla de la Juventud.

Keywords:

ocular myasthenia gravis, pre-natal care, pregnant women.

Abstract

Myasthenia gravis is an autoimmune disease of the motor end-plate of the striated muscle, characterized by fluctuant muscular fatigue and  weakness. Its prevalence is around 5 cases per 100 000 persons. The  reported patient presented symptoms limiting the muscles near the eye. This entity is named ocular myasthenia gravis. Its incidence in pregnancy is infrequent. It is reported the case of a female patient,  aged 23 years, attended in the Infertility Consultation of the municipality Isla de la Juventud. The case was consulted with several medical specialties. The delivery was produced by emergency cesarean  section, applying regional anesthesia, due to the worrying fetal  status. The newborn had good apgar score and weight. Mother and child showed satisfactory evolution during the postpartum period.

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References

1. Álvarez LLanes R, Casas Díaz CA. Miastenia grave y embarazo. Presentación de tres casos. Mediciego [revista en Internet]. 2014 Dic [citado 15 Enero 2016]; 20(Supl 2).
Disponible en: http://bvs.sld.cu/revistas/mciego/vol20_Supl%202_14/casos/T13.html

2. Midelfart Hoff J, Midelfart A. Maternal myasthenia gravis: a cause for arthrogryposis multiplex congenita. Journal of Children’s Orthopaedics [Internet]. 2015 [cited 2016 Jan 19]; 9(6): 433-435. doi:10.1007/s11832-015-0690-8.
Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661156/

3. Boldingh MI, Dekker L, Maniaol AH. An up-date on health-related quality of life in myasthenia gravis -results from population based cohorts. Health and Quality of Life Outcomes [Internet]. 2015 [cited 2016 Jan 19]; 13:115.
doi:10.1186/s12955-015-0298-1.
Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522107/

4. Naranjo Fernández RM, Estévez Miranda Y, Méndez Sánchez TJ, Dorrego Oduardo, M D, Rúa Martínez R. Miastenia grave y miastenia grave ocular. Rev Cub Oftal [revista en Internet]. 2013 [citado 15 Enero 2016]; 26 (Supl 1): 653-667, 2013. Disponible en: http://www.revoftalmologia.sld.cu/index.php/oftalmologia/article/view/227
http://www.medigraphic.com/pdfs/revcuboft/rco-2013/rcos131m.pdf

5. Nair AG, Patil-Chhablani P, Venkatramani DV, Gandhi RA. Ocular myasthenia gravis: A review. Indian Journal of Ophthalmology [Internet]. 2014 [cited 2016 Jan 11]; 62(10):985-991. doi:10.4103/0301-4738.145987.
Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278125/?report=classic

6. Flores PH, Rodríguez MO, Flores PY, Rodríguez GJN. Crisis miasténica asociada a influenza A H1N1. Presentación de un caso. Rev Ciencias Médicas de Pinar del Rio [revista en Internet]. 2012 [citado 11 Enero 2016]; 16(2): 287-294.
Disponible en: http://www.medigraphic.com/pdfs/pinar/rcm-2012/rcm122y.pdf

7. Briones-Vega CG,Viruez-Soto JA, Vallejo-Narváez CM, Tórrez-Morales F, Briones-GarduñoJC,DíazdeLeón-PonceMA. Plasmaféresis en miastenia grave y embarazo.
Rev Asoc Mex Med Crit y Ter Int [revista en Internet]. 2015 Ene-Mar [citado 18 Enero 2016]; 29(1): 46-49.
Disponible en: http://www.medigraphic.com/pdfs/medcri/ti-2015/ti151h.pdf

8.Sikka P, Joshi B, Aggarwal N, Suri V, Bhagat H. Distinguishing Myasthenia Exacerbation from Severe Preeclampsia: A Diagnostic and Therapeutic Challenge. Journal of Clinical and Diagnostic Research: JCDR [Internet]. 2015 [cited 2016 Jan 18]; 9(8):QD05-QD06. doi:10.7860/JCDR/2015/12789.6357.
Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576596/

9. Fernandes Oliveira E, Nacif SR, Alves Pereira N. Sleep disorders in patients with myasthenia gravis: a systematic review. Journal of Physical Therapy Science [Internet]. 2015 [cited 2016 Jan 18]; 27(6):2013-2018. doi:10.1589/jpts.27.2013. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500033/?report=classic

10. Suzuki S, Murai H, Imai T. Quality of life in purely ocular myasthenia in Japan. BMC Neurology [Internet]. 2014 [cited 2016 Jan 13]; 14:142. doi:10.1186/1471-2377-14-142. Available from:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4088302/?report=classic

11. Elsais A, Wyller VB, Loge JH, Kerty E. Fatigue in myasthenia gravis: is it more than muscular weakness? BMC Neurology [Internet]. 2013 [cited 2016 Jan 13]; 13:132. doi:10.1186/1471-2377-13-132. Available from:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852076/?report=classic

12. Chaudhry SA, Vignarajah B, Koren G. Myasthenia gravis during pregnancy. Canadian Family Physician[Internet]. 2012 [cited 2016 Jan 13]; 58(12):1346-1349.
Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520659/

13. Berlit S, Tuschy B, Spaich S, Sütterlin M, Schaffelder R. Myasthenia Gravis in Pregnancy: A Case Report. Case Reports in Obstetrics and Gynecology [Internet]. 2012 [cited 2016 Jan 13]; 2012:736024. doi:10.1155/2012/736024.
Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335651/

Published

2017-03-24

How to Cite

1.
García Odio AA, Ravelo Nápoles S, Rives González Y, Álvarez Bolivar D. Pregnant woman with ocular myasthenia gravis. A case report. Rev Méd Electrón [Internet]. 2017 Mar. 24 [cited 2025 Feb. 2];39(2):338-45. Available from: https://revmedicaelectronica.sld.cu/index.php/rme/article/view/1794

Issue

Section

Presentation of cases