Evaluation of response to chemoradiotherapy in non-small cell lung carcinomas in early stages
Keywords:
lung cancer, response assessment, early stages, chemoradiotherapyAbstract
Introduction: Lung cancer is the most common cause of death from malignant diseases in the world. The response rate to treatment is poor even in the initial stages and depends on several elements.
Objective: To evaluate the response to chemoradiotherapy in lung carcinomas in early stages according to smoking habit, histology and clinical stage at diagnosis.
Materials and method: An analytical, cross-sectional, retrospective evaluation study was carried out; the universe consisted of 45 patients with a cytohistological diagnosis of non-small cell lung cancer in stages from IA to IIIA, who received first-line treatment with chemoradiotherapy, attended at the Provincial Cancer Center of Matanzas, in the period of January 2017 to December 2019.
Results: A complete response was obtained in 36.6% of non-smokers and in 25% of smokers. Regarding complete response to chemoradiotherapy of lung tumors according to histology, in adenocarcinomas it was 10%, in epidermoids, 22.6%, and in adenosquamous cell, 50%. In stages IA-IB, 50% of the cases presented a complete response, in stages IIA-IIB, 37.5%, while in IIIA partial response predominated.
Conclusions: The best percentages of complete response were obtained in non-smokers, with adenosquamous histology type and in stages IA-IB.Downloads
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