Characterization of patients with reactive serology. A five-year study

Authors

Keywords:

syphilis, congenital syphilis, syphilis serodiagnosis

Abstract

Introduction: The Venereal Diseases Research Laboratory test is a nontreponemal serological test, whose reactive result is useful in the diagnosis of syphilis. However, it is not specific as it is reactive due to multiple causes.

Objective: To characterize the patients who attended the consultation with reactive serology according to variables of interest for the study.

Materials and methods: A clinical, descriptive, cross-sectional study was conducted in the Teaching Policlinic Aquiles Espinoza Salgado in the municipality of Las Tunas, Cuba. The universe was 232 patients with reactive serology during the period from January 2018 to December 2022. The variables studied were: age, sex, reason for serology, sexual orientation, causes of reactive test and diagnostic criteria in cases of reactive test due to syphilis. The information obtained was presented in tables and the results were shown in percentages.

Results: There was a predominance of heterosexuals (93,5%), preoperative check-up as the reason for performing the test (24,6%), male sex (53%), age group between 25 and 59 years (66,4%), and unification of the three criteria for the diagnosis of syphilis (56,8%). 53,9% of the tests showed syphilis.

Conclusions: Some variables were characterized in patients with a reactive test, highlighting that in most of them the cause was syphilis. The test was performed mainly due to causes not related to syphilis. Likewise, the prevailing diagnostic criterion for confirming syphilis was the unification of the three criteria.

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References

1. Rodríguez-Granger J, Espadafor López B, Cobo F, et al. Actualización en el diagnóstico de las infecciones de transmisión sexual. Actas Dermosifiliogr [Internet]. 2020 [citado 12/01/2023];111(9):711-24. Disponible en: https://www.actasdermo.org/es-actualizacion-el-diagnostico-infecciones-transmision-articulo-S0001731020302350

2. Ministerio de Salud Pública. Plan estratégico nacional para la prevención y control de las ITS, el VIH y las hepatitis. 2019-2023. La Habana: MINSAP; 2019.

3. James WD, Elston DM, Treat JR, et al. Andrews' Diseases of the Skin [Internet]. Filadelfia: Elsevier; 2016 [citado 12/01/2023]. Disponible en: https://www.academia.edu/38730349/Andrews_Diseases_of_Skin_12E_2016_PDF_medbooksvn

4. Galán Montemayor JC, Lepe Jiménez JA, Otero Guerra L, et al. Diagnóstico microbiológico de las infecciones de transmisión sexual y otras infecciones genitales [Internet]. Madrid: Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica; 2016 [citado 12/01/2023]. Disponible en: https://seimc.org/contenidos/documentoscientificos/procedimientosmicrobiologia/seimc-procedimientomicrobiologia24a.pdf

5. Fitzpatrick JE, High WA. Urgencias dermatológicas. Diagnóstico sintomático [Internet]. Barcelona: Elsevier; 2018 [citado 12/01/2023]. Disponible en: https://www.berri.es/pdf/URGENCIAS DERMATOLÓGICAS, Diagnóstico sintomático + Contenido adicional online/9788491133636

6. Jameson JL, Fauci AS, Kasper DL, et al. Harrison. Principios de Medicina Interna [Internet]. Nueva York: McGraw-Hill Medical; 2016 [citado 12/01/2023]. Disponible en: https://accessmedicina.mhmedical.com/book.aspx?bookID=2461

7. Fabiola Raffaeli R. Sífilis. En: Ingratta SMB, Manzo LB, Caseiro GM. Dermatología. Pautas básicas para su aprendizaje [Internet]. La Plata: Editorial de la Univerdiad de La Plata; 2017 [citado 12/01/2023]. p.27-40. Disponible en: https://libros.unlp.edu.ar/index.php/unlp/catalog/book/728

8. Otero Guerra L, Vázquez Valdés F. Diagnóstico molecular de la sífilis. Enferm Infecc Microbiol Clin [Internet]. 2020 [citado 12/01/2023];38(S1):7-11. Disponible en: https://www.elsevier.es/es-revista-enfermedades-infecciosas-microbiologia-clinica-28-articulo-diagnostico-molecular-sifilis-S0213005X2030032X

9. Ministerio de Salud Pública. Plan estratégico nacional para la prevención y el control de las ITS y el VIH/SIDA, 2014-2018 [Internet]. La Habana: MINSAP; 2013 [citado 12/01/2023]. Disponible en: https://healtheducationresources.unesco.org/sites/default/files/resources/cuba-plan-estrategico-its_vih_sida-2014_2018.pdf

10. Arando Lasagabaster M, Otero Guerra L. Sífilis. Enferm Infecc Microbiol Clin [Internet]. 2019 [citado 12/01/2023];37(6):398-404. Disponible en: https://www.elsevier.es/es-revista-enfermedades-infecciosas-microbiologia-clinica-28-articulo-sifilis-S0213005X19300072

11. Arenas Guzmán R. Dermatología. Atlas, diagnóstico y tratamiento [Internet]. Nueva York: McGraw-Hill Medical; 2016 [citado 12/01/2023]. Disponible en: https://accessmedicina.mhmedical.com/book.aspx?bookID=2775

12. López-Jiménez EC, Rodríguez-López J, Borrego L. Chancros digitales como manifestación de sífilis primaria. Actas Dermosifiliogr [Internet]. 2021 [citado 12/01/2023];112(S1):16. Disponible en: https://www.actasdermo.org/es-chancros-digitales-como-manifestacion-sifilis-articulo-S0001731021001484

13. Lozano-Masdemont B, Úbeda-Romero A, Polimón-Olabarrieta I. Sífilis secundaria hiperpigmentada. Actas Dermosifiliogr [Internet]. 2020 [citado 12/01/2023];112(S1):20. Disponible en: https://www.actasdermo.org/es-sifilis-secundaria-hiperpigmentada-articulo-S0001731021001459

14. González-Ruiz L, Sánchez-Caminero MP, Franco-Muñoz M, et al. Lesiones orales como única manifestación de sífilis secundaria. Actas Dermosifiliogr [Internet]. 2020 [citado 12/01/2023];111(10):876. Disponible en: https://www.actasdermo.org/es-lesiones-orales-como-unica-manifestacion-articulo-S0001731020302337

15. Dirección de Registros Médicos y Estadísticas de Salud. Ministerio de Salud Pública. Anuario estadístico de salud 2019 [Internet]. La Habana: MINSAP; 2020 [citado 12/01/2023]. Disponible en: https://salud.msp.gob.cu/wp-content/Anuario/anuario_2019_edición_2020.pdf

Published

2024-03-28

How to Cite

1.
Tamayo-Mariño K, Osorio-Almeida JE, Del-Río-Boullón T, Ruz-Domínguez J. Characterization of patients with reactive serology. A five-year study. Rev Méd Electrón [Internet]. 2024 Mar. 28 [cited 2025 Jan. 23];46:e5392. Available from: https://revmedicaelectronica.sld.cu/index.php/rme/article/view/5392

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Research article

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