Stereology in placentas from twin pregnancies

Authors

Keywords:

stereology, twin, placenta, villi, fibrin, density

Abstract

Introduction: Placental dysfunction causes fetal complications; more frequently, intrauterine growth restriction and preeclampsia.

Objective: To identify the stereological pattern in twin placentas, and its relationship with chorionicity and weight of the newborn.

Methods: A descriptive study was carried out in a sample of 16 women with twin pregnancy, 25 placentas and 32 newborns. The variables weight of the newborn, number of villi, total villous surface, villous area, node area, optical density of fibrin on the villous surface and optical density of fibrin around the vessel were studied.

Results: There was a direct relationship between the number of villi and the total villous surface. In monochorionic placentas there was a predominance of low birth weight newborns. A difference is observed in the area results according to the placental type and the topographic region. In monochorionic placentas, a greater area was observed, both in the placental villus and in the syncytial nodes, with the villus area being greater in the placental periphery and the area of syncytial nodes in the region 4 cm from the umbilical cord.

Conclusions: Microscopic stereology at the perichordal level, 4 cm from the cord and at the periphery of the placental disc showed significant differences for the villus area and fibrin optical density on the villus surface. The average values for the area of syncytial nodes and the optical density of fibrin around the vessel did not show statistically significant differences. Chorionicity is a predictor of low birth weight.

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Author Biography

Rafael Gutiérrez-Núñez, Universidad de Ciencias Médicas de Granma. Granma

Doctor en Medicina Especialista de segundo grado en Embriología Máster en Ciencias de la Educación Médica Doctor en Ciencias Médicas Profesor Titular Decano de la Facultad de Ciencias Médicas Celia Sánchez Manduley

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Published

2024-07-03

How to Cite

1.
Gutiérrez-Núñez R, Leyva-Escalona O, Alarcón-Zamora D, Gutiérrez-Alarcón BM, Castillo-Alarcón DN. Stereology in placentas from twin pregnancies. Rev Méd Electrón [Internet]. 2024 Jul. 3 [cited 2025 Mar. 9];46:e5698. Available from: https://revmedicaelectronica.sld.cu/index.php/rme/article/view/5698

Issue

Vol. 46 (2024)

Section

Research article

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