Some considerations related to clinical trials

Authors

  • Katia Brito Pérez Clínica Estomatológica Docente César Escalante. Matanzas, Cuba.
  • Roberto Cañete Villafranca Centro Provincial de Higiene Epidemiología y Microbiología. Matanzas.
  • Myrna del Puerto Horta Universidad de Ciencias Médicas de Matanzas. Matanzas, Cuba
  • Maria Elena González López Instituto de Gastroenterología. La Habana, Cuba

Keywords:

clinical trial, medical ethic.

Abstract

Clinical trials are controlled and planned experiments involving human  volunteers, used to evaluate the efficacy and safeness of surgical, medical and sanitary interventions, and also to determine the  pharmacologic, pharmacokinetics or pharmacodynamic effects of new therapeutic products, including their adverse reactions study. Considered the paradigm of the epidemiologic research, because they  are the designs that are more similar to an experiment due to the  control of the conditions under study, and because they could establish cause-effect relations, the clinical trials favor 
decision-making in public health and, beginning from the moment of the  implementation of their results, they contribute to the increase of  the life quality of human beings wherever they live. The priority of  health care decision-makers should be seeing for their correct design, evaluation and following-up by the scientific councils and research  ethic committees, and also for the adequate interpretation of the results and their publication.

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Author Biographies

Katia Brito Pérez, Clínica Estomatológica Docente César Escalante. Matanzas, Cuba.

Doctora en Estomatología. Especialista de Primer Grado en  Estomatología  General Integral y en Periodoncia. Diplomado en  Promoción y Educación  para la Salud. Profesor Asistente. Investigador  Agregado.

Roberto Cañete Villafranca, Centro Provincial de Higiene Epidemiología y Microbiología. Matanzas.

Doctor en Ciencias Médicas. Médico Especialista de Segundo Grado en  Microbiología. Máster en Parasitología. Diploma en Gastroenterología,  en  Promoción y Educación para la Salud y en Dirección. Investigador  Titular.  Profesor Titular

Myrna del Puerto Horta, Universidad de Ciencias Médicas de Matanzas. Matanzas, Cuba

Doctora en Estomatología. Especialista de Primer Grado en  Estomatología  General Integral y en Cirugía Maxilofacial. Profesor  Asistente.  Investigador Agregado

Maria Elena González López, Instituto de Gastroenterología. La Habana, Cuba

Especialista de Segundo Grado en Microbiología. Master en  Infectologia  y Enfermedades Tropicales. Diplomado en Gastroenterología  y en Dirección.  Profesor Auxiliar. Investigador Auxiliar

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Published

2016-09-28

How to Cite

1.
Brito Pérez K, Cañete Villafranca R, del Puerto Horta M, González López ME. Some considerations related to clinical trials. Rev Méd Electrón [Internet]. 2016 Sep. 28 [cited 2025 Feb. 2];38(5):719-24. Available from: https://revmedicaelectronica.sld.cu/index.php/rme/article/view/1628

Issue

Vol. 38 No. 5 (2016)

Section

Opinion article

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