Maculopathy in bull’s eye due to the use of chloroquine. Presentation of a case
Keywords:
maculopathy, chloroquine, visual impairment.Abstract
A case is reported of a patient with maculopathy in bulls’ eye associated to the use of chloroquine. The use of chloroquine associated with rheumatologic diseases can cause retinal damage related to the dose and the time of treatment evolution. It can cause from mild visual impairment to irreversible vision damage depending on the time the diagnosis is made. A 72-year-old female patient is presented with a diagnosis of rheumatoid arthritis for 21 years and treatment with chloroquine for 15 years. She assisted the consultation with a slow and progressive bilateral vision decrease; at the ophthalmological examination of the fundus a maculopathy in bull’s eye was diagnosed, later confirmed by auto fluorescence and optical coherence tomography studies.
Downloads
References
2. Browling B. Kanski. Oftalmología clínica. Un enfoque sistémico. Cap. 20. 8va ed. España: Elsevier; 2016. p. 854-5.
3. Schachat Andrew P, ed. Ryan’s Retina E-book. Section 5. 6ta ed. España: Elsevier; 2017. p. 1719.
4. American Academy of Ophthalmology. Practicing Ophthalmologists Curriculum Disclaimer and Limitation of Liability. San Francisco, CA: American Academy of Ophthalmology; 2017 p. 242-7. Disponible en: https://store.aao.org/media/resources/17686372/pod_retina_dwnld.pdf.
5. Mitra RA, Mider WF. Drug Toxicity of the Posterior Segment. Cap. 89. Ento Key; 2017. p. 1534-5. Disponible en: https://entokey.com/drug-toxicity-of-the-posterior-segment/.
6. Cukras C, Huynh N, Vitale S, et al. Subjective and objective screening test for hydroxychloroquine toxicity. Ophthalmology. 2015; 122(2): 356-66. Citado en PubMed; PMID: 25444344.
7. Carlomagno A, Silveira G, Rebella M, et al. ¿Se pueden disminuir las dosis de hidroxicloroquina en pacientes con lupus en remisión prolongada? Rev Méd Urug [Internet]. 2018 [citado 12/03/2020]; 34(1): 152-7. Disponible en: http://www.scielo.edu.uy/scielo.php?script=sci_arttext&pid=S1688-03902018000100152.
8. Danza A, Graña D, Goñi M, et al. Hidroxicloroquina en el tratamiento de las enfermedades autoinmunes sistémicas. Rev Médica Chile [Internet]. 2016 [citado 12/03/2020]; 144(2): 232-40. Disponible en: https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000200012.
9. Tejera Santana M, Oshanahan Navarro G, García Oliva I, et al. Recomendaciones actuales en el screening de la toxicidad ocular por antipalúdicos. Arch Soc Canar Oftal [Internet]. 2015 [citado 12/03/20]; 26: 17-23. Disponible en: http://sociedadcanariadeoftalmologia.com/wp-content/revista/revista-26/26sco06.pdf.
10. Abazari A, Allam SS, Adamus G, et al. Optical coherence tomography findings in autoimmune retinopathy. Am J Ophthalmol [Internet]. 2012 [citado 12/03/2020]; 153(4): 750-6. Disponible en: https://www.sciencedirect.com/science/article/abs/pii/S0002939411007203.
11. Garza-León M, Flores Alvarado DE, Muñoz-Bravo JM. Toxicidad retiniana asociada al uso de medicamentos antipalúdicos: revisión de la literatura y presentación de un caso. Medwave [Internet]. 2016 Jun [citado 12/03/2020]; 16(5): e6471. Disponible en: https://www.medwave.cl/link.cgi/Medwave/Revisiones/RevisionClinica/6471.
12. Marmor MF, Kellner U, Lai T, et al. Retinopatía por cloroquina e hidroxicloroquina. Ophthalmology [Internet]. Argentina: Intramed; 2016 [citado 12/03/2020]. p. 1386-94. Disponible en: https://www.intramed.net/contenidover.asp?contenidoid=90387.
13. Donate Tercero A, Blanco Machite C. Retinopatía por antipalúdicos. Control Oftalmológico [Internet]. España: Laboratorios Thea; 2018 [citado 12/03/2020]. Disponible en: https://www.laboratoriosthea.com/medias/thea_informacion_81.pdf.
14. Rodríguez Ferrer JM, Sáez Moreno JA, Rodríguez Hurtado FJ. Retinopatía por hidroxicloroquina: nuevas evidencias y recomendaciones. Actualidad Médica [Internet]. 2014 [citado 12/03/2020]; (792): 85-91. Disponible en: https://dialnet.unirioja.es/servlet/articulo?codigo=5347512.
15. American Academy of Ophthalmology. Retinal Degenerations Associated with Systemic Disease. San Francisco, CA: American Academy of Ophthalmology; 2014-2015.
Published
How to Cite
Issue
Section
License
All content published in this journal is Open Access, distributed under the terms of the CC BY-NC 4.0 License.
It allows:
- Copy and redistribute published material in any medium or format.
- Adapt the content.
This will be done under the following terms:
- Attribute the authors' credits and indicate whether changes were made, in which case it must be in a reasonable way.
- Non-commercial use.
- Recognize the journal where it is published.
The copyrights of each article are maintained, without restrictions.