Palliative surgical treatment of periampullary tumors, an option of long-term palliation
Keywords:
palliative surgical treatment, periampullary tumor, billioenteric derivation.Abstract
Introduction: the tumors of the duodenal-biliary-pancreatic junction or periampullary tumors correspond to a heterogeneous group of tumor. They originate inside the 2 cm of the major duodenal papilla. In unresectable tumors, the treatment should be intended for the most effective palliation. The surgical palliative treatment is intended for solving biliary, duodenal obstruction, and pain, with the aim of optimizing patients’ life quality.
Objective: to describe the behavior of the periampullary tumors palliative surgical treatment.
Materials and methods: a prospective, descriptive, observational research was carried out in patients with unresectable periampullary tumor tributary to palliative surgical treatment, in the Service of General Surgery of the University Hospital “Comandante Faustino Perez Hernandez”, of Matanzas, from January 2010 to December 2019.
Results: pancreas tumor was the most represented one. All patients were tributary to biliary palliative surgical derivation, however, gastric derivation was performed only with endoscopic confirmation of tumor infiltration or duodenal obstruction, and chemical splanchnicectomy whenever it was technically feasible and the patient’s conditions allowed it. Roux’s Y-shaped hepaticojejunostomy was the elective biliary derivation. The main surgical complication was sepsis provoking deaths.
Conclusions: surgical palliation is the election alternative with long- term better outcomes, in unresectable periampullary tumors with a good general status, contributing to better life quality.
Downloads
References
2. American Cancer Society: Key statistics for pancreatic cancer. [Internet]. April 2016[citado 09/07/20].Disponible en : http://www.cancer.org/cancer/pancreaticcancer/detailedguide/pancreatic-cancer-key-statistics.
3. López Penza PA, Ruso Martínez L. Cáncer de páncreas: epidemiología de su mal pronóstico. Rev Méd Urug [Internet]. 2017 Sep [citado 16/01/21] ; 33( 3 ): 38-57. Disponible en: http://www.scielo.edu.uy/scielo.php?script=sci_arttext&pid=S1688-03902017000300038&lng=es.http://dx.doi.org/10.29193/rmu.33.3.3.
4. Perone JA, Riall TS, Olino K. Palliative Care for Pancreatic and Periampullary Cancer. Surg Clin North Am. 2016 Dec; 96(6):1415-30. Citado en PubMed; PMID: 27865285; PMCID: PMC5119929.
5. Medrano-Guzmán R, Luna-Castillo M, Chable-Puc WJ, et al. Morbimortalidad de la pancreatoduodenectomía en pacientes con cáncer de páncreas y tumores periampulares en el Hospital de Oncología del Centro Médico Nacional Siglo XXI de 2008 a 2013. Cir Cir [Internet]. 2019[citado 12/03/20];87(1):69-78. Disponible en: https://www.medigraphic.com/cgi-bin/new/resumen.cgi?IDARTICULO=84493
6. MINSAP. Anuario Estadístico de Salud 2018 [Internet]. La Habana:MINSAP; 2019[citado 12/03/20] . Disponible en: URL:http://salud.msp.gob.cu/?tag=anuario-estadistico-de-salud
7. Macarulla T. Cáncer de vía biliar[Internet]. España: Sociedad Española de Oncología Médica; 2019[citado 03/02/20]. Disponible en:
https://seom.org/info-sobre-el-cancer/via-biliar?showall=1
8. Ramia JM, Villar J, Palomeque A, et al. Adenocarcinoma de duodeno. Rev Cir Española [Internet]. 2005[citado 03/02/20]; 77(4):208-12. Disponible en: https://www.elsevier.es/es-revista-cirugia-espanola-36-articulo-adenocarcinoma-duodeno-13073289
9. Zheng-Pywell R, Reddy S. Ampullary Cancer. Surg Clin [Internet]. 2019[09/06/20];99(2):357-67.Disponible en : https://www.sciencedirect.com/science/article/abs/pii/S0039610918301713?via%3Dihub
10. Morales Saavedra JL. Tratado de Cirugía General. En: Chan C, Staufert Gutiérrez DL, Del Ángel Millán G, et al. Cáncer de páncreas[Internet]. México: Editorial El Manual Moderno; 2017[09/06/20].p. 1432-9.Disponible en: https://www.freelibros.me/libros/tratado-de-cirugia-general-3ra-edicion-jose-luis-morales-saavedra-volumen-i-y-ii
11. Dudeja V, Christein JD, Jensen EH, et al. Páncreas exocrino. En: Townsend CM, Mark Evers B, Beauchamp RD, et al. Sabiston Tratado de Cirugía. Fundamentos biológicos de la práctica quirúrgica moderna. Capítulo 55 [Internet]. Barcelona: Editorial Elsevier. 2018[09/06/20]. p.1520-55.Disponible en : https://www.elsevier.com/books/sabiston-tratado-de-cirugia/townsend/978-84-9113-132-8
12. McIntyre RC, Schulick RD. Toma de Decisiones en Cirugía. En: Ven Fong Z, Keith D, Lillemoe. Carcinoma periampular[Internet]. España: Editor Elsevier Health Sciences. 2020[09/06/20]. p.504. Disponible en: https://tienda.elsevierhealth.com/toma-de-decisiones-en-cirugia-9788491137122.html
13. Fisher WE, Andersen DK, Windsor JA, et al. Pancreas. En: Brunicardi FC. Schwartz’s. Principles of Surgery. Capítulo 33 [Internet] . United States: McGraw-Hill Education; 2019[09/06/20]. p.1429-1504.Disponible en : https://accessmedicine.mhmedical.com/content.aspx?bookid=2576§ionid=216216083
14. Borie F. Derivación biliodigestiva quirúrgica. En: Jean François Gigot. Cirugía de las vías biliares. Capítulo 6 [Internet]. Barcelona: Editorial Elesevier MASSON; 2007[09/06/20]. p.77-90.Disponible en: https://www.elsevier.com/books/cirugia-de-las-vias-biliares/9788445816431
15. Rebours V. Cribado de cáncer de páncreas: a quién y cómo. En: Gines A, De Madaria E. Enfermedades Comunes del páncreas. Capítulo 8 [Internet]. España: Editorial Elsevier; 2015[09/06/20]. p.119-32.Disponible en: https://www.elsevier.com/books/enfermedades-comunes-del-pancreas/unknown/978-84-9022-673-5
16. Galiano Gil JM, Hernández Ortiz Y. La hepaticoyeyunostomía en el tratamiento de las afecciones hepatobiliopancreáticas. Rev Cub Cir [Internet]. 2016[09/06/20]; 55(2):[aprox. 0 p.]. Disponible en: http://www.revcirugia.sld.cu/index.php/cir/article/view/399
17. Jackson PG, Evans SR. Sistema Biliar. En: Townsend CM, Mark Evers B, Beauchamp RD, et al. Sabiston Tratado de Cirugía. Fundamentos biológicos de la práctica quirúrgica moderna. Capitulo 54[Internet]. Barcelona: Editorial Elsevier; 2018[09/06/20]. p.1482-1519.Disponible en: https://www.elsevier.com/books/sabiston-tratado-de-cirugia/townsend/978-84-9113-132-8
18. López Fabila DA, García Flores A, Díaz Téllez J, et al. Derivación bilioentérica en un centro académico de referencia estatal en México. Cir Gen [Internet]. 2015[citado 13/03/20]; 37(3-4):82-90. Disponible en: https://www.medigraphic.com/cgi-bin/new/resumen.cgi?IDARTICULO=65752
19. Rodríguez-Montes JA. Complicaciones de la cirugía general y del aparato digestivo. Rev Cir Esp [Internet]. 2001[citado 12/03/20]; 69(3): 197. Disponible en: https://www.elsevier.es/es-revista-cirugia-espanola-36-articulo-complicaciones-cirugia-general-del-aparato-11000110
20. Martos Benítez FD, Guzmán Breff BI, Betancourt Plaza I, et al. Complicaciones posoperatorias en cirugía mayor torácica y abdominal: definiciones, epidemiología y gravedad. Rev Cubana Cir [Internet]. 2016[citado 12/03/20]; 55(1):40-53. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-74932016000100005
Published
How to Cite
Issue
Section
License
All content published in this journal is Open Access, distributed under the terms of the CC BY-NC 4.0 License.
It allows:
- Copy and redistribute published material in any medium or format.
- Adapt the content.
This will be done under the following terms:
- Attribute the authors' credits and indicate whether changes were made, in which case it must be in a reasonable way.
- Non-commercial use.
- Recognize the journal where it is published.
The copyrights of each article are maintained, without restrictions.