Investigation about the chromosome disorder by means of ultrasonographic scorers in the first trimester.

Abstract

The ultrasonographic scorers of the first trimester are now described as a useful tool to select patients with risks of chromosomes disturbances, that is why we evaluate their benefits in our population, taking into consideration that its employment could have a future impact in the reduction of these affections. In the prospective study in which the Heart Case Fetal frequency, the Nape translucent and the Nasal bone were valued in all pregnants who came to consult themselves between the 11 and the 13 weeks. In all TN cases = 3mm or with 2 or more positives scorers there were Cytogenetics prenatal diagnosis. In the finish pregnancies the clinic inspections of the new born indicate the Cariotype if it was necessary. In the interrupted pregnancies an anatomopathology and chromosome studies were made. 625 fetus were evaluated and 3 aneuploidies were presented. 31 cases were observed with some positive scorers and in this group 2 of the 3 chromosome aberrants were found. We calculate each score to select women with risks in having affected children. The Nape translucent demonstrated the highest sensibility (66.6%) and the Heart Case Fetal frequency as well as the Nasal Bone showed a sensibility of 33.3%. We consider that they are a useful tool in our environment.