Importance of the heart arrhythmias induced by thioridazine in geriatric ages

Authors

  • Danieyi Moral Valls Hospital Clínico Quirúrgico Docente Amalia Simoni. Camagüey. https://orcid.org/0000-0002-3629-6216
  • Odalmis Chacón Borrero Hospital Clínico Quirúrgico Docente Amalia Simoni. Camagüey.
  • Alfredo Enrique Arredondo Bruce Hospital Clínico Quirúrgico Docente Amalia Simoni. Camagüey.

Keywords:

psychosis, thioridazine, cardiovascular changes, electrocardiographic changes.

Abstract

Introduction: mental incapacity, tightly related to the life expectancy increase, is considered one of the most serious problems to afford in the current century. It brings about the increase of the prescription of anti-psychotic agents, like thioridazine, tending to become a health problem because of causing arrhythmias that are occasionally life-threatening. It is still unknown in what level these alterations are responsible for several sudden deaths in persons who took these drugs.
Objective: to identify which are the clinical and electrocardiographic alterations in patients using thioridazine as drug of choice in psychiatric disorders.
Materials and methods: a descriptive study was carried out in all patients who attended the Geriatric Service taking thioridazine in any doses during the period from March 2017 to March 2018.
Results: female elder people aged 60-74 years predominated, with secondary school scholarship, finding a relationship with the double function of women in the current society, and the high level of scholarship among Cuban citizen. Arterial hypertension and diabetes antecedents predominated, and also palpitations related to the increase of His bundle blockade observed in electrocardiograms. There were no deaths.
Conclusions: low doses of the drug should be used for a short time and under electrocardiographic supervision.

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Published

2019-10-30

How to Cite

1.
Moral Valls D, Chacón Borrero O, Arredondo Bruce AE. Importance of the heart arrhythmias induced by thioridazine in geriatric ages. Rev Méd Electrón [Internet]. 2019 Oct. 30 [cited 2025 Jul. 1];41(5):1192-204. Available from: https://revmedicaelectronica.sld.cu/index.php/rme/article/view/3152

Issue

Vol. 41 No. 5 (2019)

Section

Research article

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