Neuroimaging in AIDS
Keywords:
TOMOGRAPHY, EMISSION-COMPUTED, MAGNETIC RESONANCE IMAGEN, NUCLEAR MAGNETIC RESONANCE, ACQUIRED IMMUNODEFICIENCY SYNDROME, HIV INFECTINS, AIDS-RELATED OPPORTUNISTIC INFECTIONS, HUMAN, ADULTAbstract
Up to 90 % of those infected by the Human Immunodeficiency Virus will have Central Nervous System (CNS) involvement. CNS injury by HIV and its complications produce neuropathological, physiologic, and metabolic abnormalities that are detectable noninvasively by modern neuroimaging methods. Modern structural imaging involving Computed Tomography and Magnetic resonance, plays a cristical role in the clinical evaluation and treatment of HIV positive patients with new onset neurological sympotoms. The advanced functional and metabolic imaging probes (Magnetic resonance spectroscopy, functional magnetic resonance, Single photon emission computed tomography and Positron emission tomography) may contribute to the diagnostic specificity of the structural findings and are providing an insight into the pathobiology of HIV related dementia. We review the effects of HIV on the brain as revealed by advanced neuroimaging.Downloads
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