Comparison between the use of lyophilized morphine by subarachnoid and epidural via
Keywords:
MORPHINE, PAIN, POSTOPERATIVE, ANALGESIA, EPIDURAL, HUMAN, ADULTAbstract
The morphine is the opioid most frequently used by neuroaxial via to provide postsurgery analgesia; nonetheless, there are controversies about the analgesia level and about the incidence of adverse reactions. The objective was evaluating and comparing the analgesia obtained administering lyophilized morphine by subarachnoid and epidural via. We carried out an analytic, prospective, randomized study in 100 patients ASA I y ASA II, subjected to retropubic prostatectomy, divided into two groups . The patients of the Group E received 2 mg of lyophilized morphine, and those in Group S, 0, 1 mg of the same analgesic. The analgesia was evaluated with the application of the Visual Analogue Scale at the 1 st , 8 th , 16 th , 24 th and 36 th hours after recuperation; the complications were evaluated too. In both groups, the Visual Analogue Scale value was >4 after the 24th hour of recuperation. There was not intense pain at any moment. There was a bigger quantity of patients with pain in the Group E, and also a bigger demand of analgesics. The media postsurgery analgesia time was similar in both groups. Although the intensity of pain and the analgesic consume of the Group S was fewer, they also presented more complications.Downloads
References
Granizo ME. Estudio abierto multicéntrico con tramadol de acción retardada en el manejo del dolor crónico no canceroso y por cáncer. Rev Inst Invest Méd Quir 2002;1(2):38-43
Ashburn MA, Ready LB. Postoperative Pain. In Bonica's Management of Pain. Loesser JD: Ed. Third Edition. Lipincott.Philadelphia: Williams & Wilkins;2001.p. 765-79.
González MI, Field MJ, Bramwell S, McCleary S, et al. Ovariohysterectomy in the rat: a model of surgical pain for evaluation of pre-emptive analgesia? Pain 2000; 88 (1):79-89.
Paladino AM. El dolor postoperatorio no se debe tratar. Memorias XXIV Congreso Mex Anestesiol 2000; 12 (1): 135-6.
Lacasie HJ. Analgesia postoperación cesárea. Rev Arg Anest 2000;58(1): 391-93.
Huerta JC. Uso de bupuvacaína y morfina espinal para el manejo del dolor postoperatorio en cirugía ginecológica. Rev Mex Anest 2001;1 (4): 103-8.
Ready LB. Acute Perioperative Pain. En Miller RD (ed): Anestesia 5ª. ed. Philadelphia: Churchill Livingstone; 2000. p. 2328-34 .
Rawal N. Spinal opioids for acute pain management. En Raj PP (ed) Practical Management of Pain: 3ª ed. St. Louis: Mosby ; 2000. p. 689-703.
Omahony S, Coyle N, Payne R. Current management of opiod related side effects. Oncology 2001;15 (1): 61-73.
Reiz S, Bennett S. Cardiovascular effects of epidural anaesthesia. Anaesthesiology 1993; 6(5):813-18.
Duale C, Frey C. Epidural vs intrathecal morphine for postoperative analgesia after caesarean section. Br J Anaesth 2003; 91 (5): 690-4.
Torres JC. Uso de droperidol como agente antiemético por vía peridural en combinación con morfina para el control del dolor postoperatorio. Rev Mex Anest 2001;1:201-7.
Quiroga OJ, Hernández JR, Tenoplala S, Castillejos V, Porras R, Piver MG. Estudio comparativo entre bupivacaina-morfina-clonidina por vía epidural en la analgesia postoperatoria de pacientes sometidas a cesárea. Rev Soc Esp Dolor 2003;10:135-44.
Kissin HI, Weiskof RB. Preemptive analgesia. Anesthesiology 2000;93(4):714-23.
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