Scientific evidence on the antibacterial activity of Rosemary and Japanese Mint on strains of Staphylococcus aureus
Abstract
Introduction: Scientific evidence of the use of Rosmarinus officinalis L. and Menta arvensis, grown in Cuba, as antimicrobials is very limited.
Objective: To demonstrate the antibacterial effect of Rosmarinus officinalis L. and Mentha arvensis, grown in Cuba, against clinical strains of methicillin-resistant Staphylococcus aureus that produce bacterial skin infections and against reference strains
Methods: The fluid extract was obtained by the cold maceration method. The minimum inhibitory and bactericidal concentration was determined by the tube macrodilution method.
Results: The clinical strains of methicillin-resistant Staphylococcus aureus analyzed showed a minimum inhibitory concentration of 6.25 µg/mL and a minimum bactericidal concentration of 12.5 µg/mL, against rosemary extract. The mint extracts showed the minimum inhibitory concentration at 3.1 µg/mL and minimal bactericidal at 6.25 µg/mL. The combined extract enhances the antimicrobial effect.
Conclusions: Rosemary and mint extracts, and their combination, show in vitro antimicrobial activity on clinical strains of methicillin-resistant Staphylococcus aureus and on reference strains. This evidence points to future opportunities for the development of dermatological drugs from medicinal plant extracts.
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