Clinical-imaging correlation of squamous cell carcinoma associated with schistosomiasis: about a case
Keywords:
schistosomiasis; bilharzia; M-VAC treatmentAbstract
A case of a 31-year-old patient with a bladder tumor associated to schistosomiasis, treated at the Central Hospital of Nampula, Mozambique, was studied. After having carried out the study, the surgical treatment was performed, which consisted of partial cystectomy with left ureteral re-implantation at the end of December 2021. Pathological anatomy describes the presence of squamous cell carcinoma of the bladder, with areas of abscedation and necrosis, in addition to the presence of eggs and larvae of Schistosoma hematobium; there are also areas of cystitis. Surgical session edges free of tumor. He was referred to the oncology service taking the M-VAC treatment regimen every 21 days for three months, showing good progress. He continues to be followed up every 6 months in the urology clinic where ultrasonography, PA Chest X-ray and progressive cystoscopy are repeated. Until now, the patient is free of tumor recurrence, there is no presence of cystitis, and the calcifications of the bladder mucosa have decreased considerably.
Downloads
References
1. Iglesias-Osores S, Elorreaga P, Failoc-Rojas VE. Schistosomiasis: problema de salud para vigilar. REM [Internet]. 2019 [accessed 2021/09/25];4(4):161-2. Available from: https://rem.hrlamb.gob.pe/index.php/REM/article/view/249
2. Ogongo P, Nyakundi RK, Chege GK, et al. The road to elimination: current state of schistosomiasis research and progress towards the end game. Front Immunol [Internet]. 2022 [accessed 2024/02/13];13:846108. Available from: https://pubmed.ncbi.nlm.nih.gov/35592327/
3. Lackey EK, Horrall S. Schistosomiasis. En: Ackley WB, Adolphe TS, Aeby TC, et al. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 [accessed 2024/02/13]. Available from: https://pubmed.ncbi.nlm.nih.gov/32119321/
4. León-Ramos OL, Arencibia-Díaz L, García-Reyes AA, et al. La esquistosomiasis como factor de riesgo del cáncer de vejiga. Hospital Central de Nampula, Mozambique. Rev Méd Electrón [Internet]. 2023 [accessed 2024/03/14];45(1):70-82. Available from: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1684-18242023000100070&lng=en
5. Orish VN, Morhe EKS, Azanu W, et al. The parasitology of female genital schistosomiasis. Curr Res Parasitol Vector Borne Dis [Internet]. 2022 [accessed 2024/03/14];2:100093. Available from: https://pubmed.ncbi.nlm.nih.gov/35719849/
6. Gryseels B, Polman K, Clerinx J, et al. Human schistosomiasis. Lancet. 2006;368(9541):1106-18. DOI: 10.1016/S0140-6736(06)69440-3.
7. Salas-Coronas J, Vázquez-Villegas J, Villarejo-Ordóñez A, et al. Hallazgos radiológicos en pacientes con esquistosomiasis importada. Enferm Infecc Microbiol Clin [Internet]. 2013 [accessed 2024/03/14];31(4):205-9. Available from: https://pubmed.ncbi.nlm.nih.gov/22683176/#:~:text=Enferm%20Infecc%20Microbiol,2012%20Jun%209
8. Jiménez Coronel V, Díaz Rubia L, Martínez Huertas C, et al. Manifestaciones radiológicas de la esquistosomiasis. Revisión del tema. Seram [Internet]. 2018 [accessed 2024/03/14]. Available from: https://piper.espacio-seram.com/index.php/seram/article/view/924
9. Organización Mundial de la Salud. Esquistosomiasis [Internet]. Ginebra: OMS; 2023 [accessed 2024/03/14]. Available from: https://www.who.int/es/news-room/fact-sheets/detail/schistosomiasis
10. Kokaliaris C, Garba A, Matuska M, et al. Effect of preventive chemotherapy with praziquantel on schistosomiasis among school-aged children in sub-Saharan Africa: A spatiotemporal modelling study. Lancet Infect Dis. 2022;22(1):136-49. DOI: 10.1016/S1473-3099(21)00090-6.
11. Jagtap SV, Jagtap SS, Kaur P, Vartak S: Squamous Cell Carcinoma of the Urinary Bladder: Clinicopathological and Molecular Update -Review. Ann Urol Oncol 2021; 4(1): 10-17. DOI: 10.32948/auo.2021.10.11.
12. Dotson A, May A, Davaro F, Raza SJ, Siddiqui S, Hamilton Z: Squamous cell carcinoma of the bladder: poor response to neoadjuvant chemotherapy. Int J Clin Oncol 2019, 24(6): 706-11. DOI: 10.1007/s10147-019-01409-x.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Revista Médica Electrónica (Medical Electronic Journal)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All content published in this journal is Open Access, distributed under the terms of the CC BY-NC 4.0 License.
It allows:
- Copy and redistribute published material in any medium or format.
- Adapt the content.
This will be done under the following terms:
- Attribute the authors' credits and indicate whether changes were made, in which case it must be in a reasonable way.
- Non-commercial use.
- Recognize the journal where it is published.
The copyrights of each article are maintained, without restrictions.
