Experiences in conducting clinical trials in the province of Matanzas. 2005-2012

Abstract

Clinical trial is a methodology suitable to evaluate a therapeutic intervention in human beings, commonly known as the golden standard In the decade of the 90es, the province of Matanzas was inserted in the  clinical trial national net, and there have being evaluated ample impact products  in coordination with the Clinical Trial National Coordinating Center (CENCEC, in Spanish). We developed a retrospective descriptive study with the aim of evaluating the social impact of the clinical trials in the province of Matanzas during the period 2005-2012. In the analyzed period there were finished 11 clinical trials and there are 24 more in course; there are a total of 11 evaluated products. The total number of clinical sites-clinical trial is 9, participating 196 researchers, and 443 patients through the period. The promoting centers with more participation are: the Center of Molecular Inmunology, the National Center of Farming Health, the Ozone Technical Office and the Center of Genetic Engineering and Biotechnologies. The drugs evaluated in the clinical trials were against the following diseases: cancer, respiratory distress, bronchial asthma and predialysis. Most of the products evaluated in national clinical trials are indicated against cancer, and its most representative location is the lungs; other locations are prostate glands, esophagus, kidneys and mammas. The positive influence in the National Health System is expressed in benefits like improvement in health indicators, changes in the medical care patterns of the disease in which the product was evaluated, and formation and improvement of the human resources participating in the trial.