Antioxidant enzymes in saccharose-induced hyperglycemia and hyperlipidemia in Wistar rats

Authors

  • Alcides González Gil Universidad de Ciencias Médicas de Matanzas. Matanzas, Cuba.
  • Yisel González Madariaga Universidad de Ciencias Médicas de Villa Clara. Villa Clara, Cuba.
  • Danay Heredia Ruiz Universidad de Ciencias Médicas de Villa Clara. Villa Clara, Cuba.
  • Douglas Fernández Caraballo Universidad de Ciencias Médicas de Villa Clara. Villa Clara, Cuba.
  • Marianela Ballesteros Hernández Universidad de Ciencias Médicas de Villa Clara. Villa Clara, Cuba.

Keywords:

oxidative stress, free radicals, antioxidant enzymes, catalase, dismutase superoxide.

Abstract

The work we accomplished evaluated the activity of the catalase antioxidant and dismutase superoxide enzymes in the experimental model of saccharose induced hyperlipidemia in Wistar rats, for what we determined the glicemia and plasmatic fluids and the levels of dismutase superoxide and catalase specific enzymatic activity. There they were significant increases in glicemia and triacylglycerides related with a saccharose-rich diet. At the fourth month of the study we observed an increase of the enzymes in the group with a saccharose-rich diet, with significant increases only for the catalase. It was observed a strong correlation between the triacylglyceride levels of the studied group in the last month of experimentation and the values obtained in the catalase enzymatic activity.

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Published

2013-03-15

How to Cite

1.
González Gil A, González Madariaga Y, Heredia Ruiz D, Fernández Caraballo D, Ballesteros Hernández M. Antioxidant enzymes in saccharose-induced hyperglycemia and hyperlipidemia in Wistar rats. Rev Méd Electrón [Internet]. 2013 Mar. 15 [cited 2025 Jan. 13];35(2):95-103. Available from: https://revmedicaelectronica.sld.cu/index.php/rme/article/view/15

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Section

Research article

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