Role of the oxygen reactive metabolites in periodontal diseases.

Abstract

The periodontal disease is one of the diseases that most affect the human being anywhere in the world. In its pathogenesis and development take part several risk facts, some of them difficult to control. The oxygen free radicals or reactive metabolites are present and play a very important role in the worsening of this entity. It is necessary to know the conceptual aspects related with the generating mechanisms of the forms of the oxygen reactive metabolites and its consequences at the molecular and cellular levels by its action on the lipids, proteins and nucleic acids, and also on the antioxidant defence system the organism has for its protection. To be able of measuring the stress or the level of oxidative damage in patients with periodontal affections to establish a predictive diagnostic and to act early to avoid the advance of the disease, would be a step to implement in the immediate future. In this work we expose these reflections based on the studies carried out in Cuba and in other pats of the world with good results.