Gestational diabetes: need for preconception genetic counseling in Matanzas

Authors

Keywords:

gestational diabetes, pregnancy, diabetes mellitus, genetic counselling, genetic risk

Abstract

Introduction: many pregnant women attended in prenatal genetic consultation come from families with diabetes mellitus and develop gestational diabetes, so they require preconception genetic counseling on risk factors, which they do not receive in many cases.

Objective: to identify family antecedents of diabetes mellitus in pregnant women who debut with gestational diabetes, without having received preconceptional genetic counseling.

Materials and methods: a retrospective descriptive study was carried out during the period 2017 to 2019 in 186 pregnant women from the municipality of Matanzas, diagnosed with gestational diabetes.

Results: 39.7 % of the pregnant with gestational diabetes came from families with diabetes mellitus; 27.02 % of them had an affected first-grade relative; maternal hereditary transmission predominated in 59.45 %; 22.58 % presented congenital defects, and 54.05 % did not received preconceptional genetic counseling.

Conclusions: not all the pregnant women with family antecedents of diabetes mellitus received preconceptional genetic counseling, which is essential to minimize the risk of gestational diabetes.

Downloads

Download data is not yet available.

References

1. World Health Organization. Definition and classification of diabetes mellitus and complications. Report of WHO consultation. Part 1: Diagnosis and classification of diabetes mellitus [Internet]. Geneva: WHO [citado 18/11/2020]; 2017. Disponible en: https://apps.who.int/iris/handle/10665/66040

2. Medina-Pérez EA, Sánchez-Reyes A, Hernández-Peredo AR, et al. Diabetes gestacional. Diagnóstico y tratamiento en el primer nivel de atención. Med Interna Méx [Internet]. 2017 Feb [citado 22/02/2020];33(1):91-8. Disponible en: http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0186-48662017000100091&lng=es

3. Martínez Leyva G, Hernández Ugalde F, Blanco Pereira ME. Intervención educativa en prevención preconcepcional de efectos embriofetales de la diabetes mellitus. Policlínico Universitario Carlos Verdugo, 2018-2019. Rev Méd Electrón [Internet]. 2021 [citado 22/05/2021];43(2):3133-46. Disponible en: https://www.revmedicaelectronica.sld.cu/index.php/rme/article/view/4092/html_867

4. Ruiz-Hoyos BM, Londoño-Franco AL, Ramírez-Aristizábal RA. Prevalencia de Diabetes Mellitus Gestacional por curva de tolerancia a la glucosa en semanas 24 a 28. Cohorte prospectiva en Armenia, Colombia, 2015-2016. Rev Colomb Obstet Ginecol [Internet]. 2018 [citado 22/06/2020];69(2):108-16. Disponible en: https://revista.fecolsog.org/index.php/rcog/article/view/3056

5. Rojas-Martínez R, Basto-Abreu A, Aguilar-Salinas CA, et al. Prevalencia de diabetes por diagnóstico médico previo en México. Salud Pública de México [Internet]. 2018 [citado14/06/2019];60(3):224-32. Disponible en: https://doi.org/10.21149/8566

6. Ramos Rangel Y, Morejón Suárez R, Cabrera Macías Y, et al. Adherencia terapéutica, nivel de conocimientos de enfermedad y autoestima en pacientes diabéticos tipo 2. Gac Med Espir [Internet]. 2018 [citado 30/02/2019];20(3):13-20. Disponible en: http://scielo.sld.cu/scielo.php?pid=S1608-89212018000300013&script=sci_arttext&tlng=en

7. Ryan DK. Early screening and treatment of gestational diabetes in high-risk women improves maternal and neonatal outcomes: A retrospective clinical audit. Diabetes Res Clin Pract. 2018;144:294-301. Citado en PubMed; PMID: 30244050.

8. Villota-Burbano D, Casillas-Barrera M, Morales-Morales MP, et al. Desenlace materno-fetal en pacientes con diagnóstico temprano o tardío de diabetes gestacional. Ginecol Obstet Mex [Internet]. 2019 [citado25/09/2020];87(12):785-91. Disponible en: https://doi.org/10.24245/gom.v87i12.3255

9. Feghali MN, Kaleab ZA, Comer DM, et al. Pregnancy outcomes in women with an early diagnosis of gestational diabetes mellitus. Diabetes Res Clin Pract. 2018;138:177-86. Citado en PubMed; PMID: 29427694.

10. Immanuel J, Simmons D. Screening and Treatment for Early-Onset Gestational Diabetes Mellitus: A Systematic Review and Meta-analysis. Curr Diab Rep [Internet]. 2017 [citado 25/09/2020];17(1):15-25. Disponible en: https://doi.org/10.1007/s11892-017-0943-7

11. Martin-Montalvo A, Benoit-Gauthier R, López-Noriega L, et al. Transiet PAX8 expression in islets during pregnancy correlates with beta cell survival, revealing a novel candidate gene in gestational diabetes mellitus. Diabetes. 2019;68(1):109-18. Citado en PubMed; PMID: 30352879.

12. Quintero Paredes PP. La diabetes mellitus gestacional y su relación con algunos factores de riesgo en el Policlínico “Pedro Borrás Astorga”. Rev Cubana Obst Ginecol [Internet]. 2020 [citado 22/11/2020];46(3):e539. Disponible en: http://www.revginecobstetricia.sld.cu/index.php/gin/article/view/539/613

13. Cruz Hernández J, Pérez Fundora A, Yanes Quesada M, et al. Factores de riesgo de diabetes gestacional en mujeres embarazadas de una maternidad de La Habana. Rev Cubana Med Gener Integ [Internet]. 2020 [citado 14/01/2021];36(2):e1080. Disponible en: https://scielo.sld.cu/pdf/mgi/v36n2/1561-3038-mgi-36-02-e1080.pdf

14. Pinillos Patiño Y, Herazo Beltrán Y, Mendoza Charris H, et al. Relación entre la práctica de actividad física en embarazadas y diabetes gestacional: un estudio transversal. Rev Latinoamericana de Hipertensión [Internet]. 2017 [citado 18/11/2020];12(5). Disponible en: https://hdl.handle.net/20.500.12442/2343

15. Lara O’Farril LC, O’Farril Hernández LA, Martínez de Santelices Cuervo A. Interacción genoma-ambiente en la génesis de la diabetes mellitus tipo 2. Acta Méd del Centro [Internet]. 2017 [citado 18/11/2020];11(4). Disponible en: http://www.revactamedicacentro.2017.vol.11no.4.sld.cu

16. Padrón Aguilera OI, Santos Solí M, Velázquez Martínez VR, et al. Diabetes y malformaciones congénitas. Cienfuegos, 2005-2015. Medisur [Internet]. 2019 [citado 18/11/2020];17(5):633-40. Disponible en: http://medisur.sld.cu/index.php/medisur/article/view/4114

17. Blanco Pereira ME, González Gil A, Luna Ceballos EJ, et al. Epigenética y ontogenia humana, baluarte inestimable en la promoción de salud y prevención de enfermedades. Rev Méd Electrón [Internet]. 2019 [citado18/11/2020];41(4). Disponible en: http://www.revmedicaelectronica.sld.cu/index.php/rme/article/view/3048/4391

18. Rodríguez Nájera GF, Camacho Barquero FA, Umaña Bermúdez CA. Relación epigenética entre la desnutrición materna y la diabetes mellitus tipo 2. Rev Médica Sinergia [Internet]. 2019 [citado 18/11/2020];4(10). Disponible en: http://doi.org/10.31434/rms.v4i10.278

19. Luna Ceballos EJ, Castro López M, León Luna D. La epigenética en el curso de la vida: un reto en la formación continua del personal de salud. Rev Méd Electrón [Internet]. 2020 [citado 18/12/2020];42(1). Disponible en: http://www.revmedicaelectronica.sld.cu/index.php/rme/article/view/3282/html_735

20. Sessarego Tabja S. La importancia del asesoramiento genético para el diagnóstico genético preimplantacional de aneuploidías (PGT-A). Rev peruana ginecol obstet [Internet]. 2019 [citado 18/11/2020];65(2). Disponible en: https://dx.doi.org/10.31403/rpgo.v65i2172

Downloads

Published

2021-12-15

How to Cite

1.
Luna-Ceballos EJ, Rodríguez-Acosta Y, Martínez-Leiva G, Blanco-Pereira ME, Perdomo-Arrién JC, Castro-López M, et al. Gestational diabetes: need for preconception genetic counseling in Matanzas. Rev Méd Electrón [Internet]. 2021 Dec. 15 [cited 2025 Jan. 10];43(6):1-10. Available from: https://revmedicaelectronica.sld.cu/index.php/rme/article/view/4454

Issue

Vol. 43 No. 6 (2021)

Section

Research article

License

All content published in this journal is Open Access, distributed under the terms of the CC BY-NC 4.0 License.

It allows:

 - Copy and redistribute published material in any medium or format.

 - Adapt the content.

 This will be done under the following terms:

 - Attribute the authors' credits and indicate whether changes were made, in which case it must be in a reasonable way.

 - Non-commercial use.

 - Recognize the journal where it is published.

 The copyrights of each article are maintained, without restrictions.

Most read articles by the same author(s)